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Thursday, May 28, 2026

CBD: Does it work? Is it safe? Is it legal? - AAMC

Cannabidiol has been used to treat insomnia, depression, anxiety, and more. But what does the science say about its safety and efficacy? And do consumers have to worry about getting into legal trouble for using marijuana’s cousin?

Cannabidiol — better known as CBD — seems to be everywhere: in gummies, lotions, oils, lollipops, vapes, toothpaste, even a high-end sports bra. It’s been touted as a treatment for such concerns as anxiety, insomnia, pain, PTSD, and depression.

And it’s increasingly popular. Last year, 64% of U.S. adults reported trying a CBD product — and nearly half of those did so at a doctor’s suggestion, according to a Forbes Health survey. In 2022, the CBD market was valued at $18 billion, and it’s expected to more than triple in the next 10 years.

But hype aside, researchers are hard at work assessing the true value of CBD — which comes from the same plant family as marijuana but doesn’t induce a high — and the varied products it has spawned.

Here’s what experts have to say about CBD’s risks and benefits — and where they see CBD use headed in the future.

Does CBD work?

The medication Epidiolex — the only CBD-based treatment approved by the U.S. Food and Drug Administration (FDA) — has been proven effective for severe seizure disorders. A twice-daily oral solution, Epidiolex has been shown to be effective in a number of clinical trials, including a 2021 study that found a median decrease in certain seizures ranging from nearly 50% to over 70%.

But some...



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