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Saturday, April 25, 2026

Semaglutide: Half of children on drug are no longer clinically obese, study finds - Insider

  • 134 children with clinical obesity were given weight-loss drug semaglutide.
  • Almost half of them lost enough weight to no longer be considered clinically obese.
  • Semaglutide, a medically-prescribed drug, is changing the face of obesity treatment, experts have said.

Almost half of children given weight-loss jab semaglutide lost enough weight to no longer be considered clinically obese, a study found.

The study, presented at the European Congress on Obesity in Dublin, is the latest in a series of trials showing the jab offers life-saving treatment to people with obesity.

Two hundred and one adolescents with clinical obesity between 12 and 18 were entered in a trial to test the effect of the weight-loss drug semaglutide, marketed under the name Ozempic when it is prescribed for diabetes and Wegovy when prescribed for weight loss.

One hundred and thirty-four of these children received a weekly dose of 2.4 milligrams of semaglutide for more than a year, alongside healthy lifestyle counseling, The Guardian reported. The rest received the same lifestyle counseling and a placebo jab.

The study found that at the end of 68 weeks of treatment, almost 45% of children who got semaglutide dropped enough weight to no longer be considered clinically obese, compared to just 12% of adolescents who received the placebo, per The Guardian.

The results are "historically unprecedented with treatments other than bariatric surgery," Aaron Kelly, a study lead and the co-director of the Center...



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